A masked ninja stalks the streets. Who is this mysterious figure?

Following the incident in the Southeast Asia Union in 2116, Shinya Kogami resumes his vagrant journey. In a small South Asian nation, Kogami rescues a bus of refugees under attack by armed guerrilla forces. Among the refugees is a young lady by the name of Tenzin, who begs Kogami to teach her how to retaliate against the enemy. Just what do the girl who wishes for revenge and the man who has exacted revenge see as they gaze upon the edge of a world from which there is no escape?

In the winter of 2117, a runaway vehicle crashes into the Public Safety Bureau Building. The driver is identified as Izumi Yasaka, a psychological counselor at the Sanctuary, a Latent Criminal Isolation Facility in Aomori Prefecture. But right before her interrogation, Inspector Mika Shimotsuki and Enforcer Nobuchika Ginoza are tasked with promptly escorting Yasaka back to Aomori. What awaits them there is a False Paradise.

2112; the summer before Akane Tsunemori was assigned to Division One of the Public Safety Bureau's Criminal Investigation Department. Teppei Sugo, an accomplished pilot of the Defense Army's 15th Integrated Task Force, joins the military operation in Okinawa. Three months later, an unmanned combat drone opens fire on the Ministry of Defense in Tokyo. Enforcer Tomomi Masaoka of CID Division One is dispatched to Sugo's military base to investigate the truth behind this case.

Villains are rampaging through Charter City and the Flex Fighters -- Jake, Ricardo and Nathan -- need your help to halt the chaos.

Defeating numerous villains in the abandoned area in Z-City but still having problems with rent money (and continued harassment from the landlady who says he's 3 months overdue), Saitama speaks with a shop owner who is being forced by a local gang to surrender his store's deed. Several other shops have gone out of business and his store is the last one; a conversation between the gang boss and one of his stooges reveal that the boss has had an impulse to buy out all the stores in the area to destroy them.